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Table 2 Comparison of synthesis data

From: ELIXYS - a fully automated, three-reactor high-pressure radiosynthesizer for development and routine production of diverse PET tracers

Radiotracer Reference Radiochemical yield (%) Duration of synthesis (min) Specific activity (GBq/μmol)
[18F]FAC Amarasekera et al. [17] 39 ± 5 (n = 13) ~240 >37
This work 31 ± 5 (n = 6) 165 37 to 44
[18F]FMAU Alauddin et al. [11] 20 to 30 210 to 240a 85.1
Mangner et al. [24] 42.1 ± 12.1 (n = 9) 160 111b
Li et al. [16] 12 ± 3 (n = 4) 150a 14.2 ± 1.2
Amarasekera et al. [17] 35 ± 6 (n = 10) ~240 >37
  This work 46 ± 1 (n = 6) 170 100 to 170
  1. Yield, synthesis duration, and specific activity of two tracers produced with the ELIXYS radiosynthesizer compared to values found in literature. aEndpoint not specified, but presumably includes HPLC purification; btime point not specified, but presumably at time of injection.