ELIXYS - a fully automated, three-reactor high-pressure radiosynthesizer for development and routine production of diverse PET tracers

EJNMMI Research

Table 1 List of unit operations available to build a synthesis sequence

Unit operation	Description of function
Initialize	Initializes hardware
TrapF18	Trap [¹⁸F]fluoride from cyclotron or preloaded external vial
EluteF18	Elute [¹⁸F]fluoride with a reagent from the cassette
Add	Add a reagent from any cassette
Evaporate	Evaporate the contents of a reactor
React	Fully seal a reaction vessel for a reaction
Transfer	Transfer solvents and reaction products from one reaction vessel to another, often using purification cartridges in between
TransferToHPLC ^a	Transfers the contents of the reaction vessel to the HPLC injection loop
ExternalAdd	Move a reactor to its add position for externally adding a reagent
Mix	Mix the contents of a reaction vessel
Install	Move a reactor to a position for reaction vessel removal and/or installation
MeasureRadiation ^a	Measures the radiation level of a given reactor