Impact of intraperitoneal and intravenous contrast media enhancement on tumor localization on SA-CT images: rats. Representative coronal slices for unenhanced CT (a) and contrast-enhanced SA-PET/CT (b and c) of a rat with multiple abdominal lesions. The animal first underwent SA-CT acquisition, was subsequently injected with a mixture of 18F-FDG and Fenestra VC, and received an intraperitoneal injection of iohexol immediately before the SA-PET/CT acquisition began. Tumors are well defined in the contrast-enhanced CT slice (yellow arrows). Also visible are the liver and the spleen (red arrow). Note that due to rapid absorption through the peritoneum, contrast media is excreted in the bladder.