From: Chronic AMPK activity dysregulation produces myocardial insulin resistance in the human Arg302Gln-PRKAG2 glycogen storage disease mouse model
Mouse Genotype
Baseline
Insulin
TGwt
0.7 ± 0.1
1.2 ± 0.1*
TGmut
0.3 ± 0.2**
0.4 ± 0.2