From: 11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains
11C-LY2428703
18F-FMPEP [22]
18F-SP203 [19]
11C-( R)-rolipram [23]
11C-NOP1A [24]
Target
mGluR1
CB1
mGluR5
PDE4
NOP
Brain peak SUV
~0.5
3 to 4
~6
2 to 2.5
5 to 7
Exposure SUV (0 to 20)
202.2
47.8
37.0
124.9
36.7
f p %
0.094
0.63
5.2
6.4
10.1
Effective exposure (E × f p)
0.19
0.30
1.9
8.0
3.7
