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EJNMMI Research

Table 2 Kinetic modeling results in humans using a two-tissue compartment model

From: 11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains

 

Compartmental distribution volume

Region

V T (mL · cm−3)

Frontal cortex

0.092 ± 0.016 (14.2%)

Temporal cortex

0.102 ± 0.010 (4.4%)

Parietal cortex

0.087 ± 0.011 (4.9%)

Caudate

0.086 ± 0.024 (22.6%)

Cerebellum

0.090 ± 0.010 (2.8%)

  1. Representative brain regions from the three human subjects. Values are mean ± SD. Standard errors are listed in parentheses and are expressed as percent (%) of the variable itself.
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