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EJNMMI Research
Figure 3 | EJNMMI Research

Figure 3

From: High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats

Figure 3

Correlations between [123 I]β-CIT SPECT/CT and immunohistochemical and behavioral data at 2 and 4 weeks post-lesion. Striatal binding of [123I]β-CIT showed high correlation to striatal (A) DAT- and (B) TH-reactive fiber densities and (C) nigral TH-reactive cell numbers at both time points. At 4 weeks, [123I]β-CIT SPECT/CT correlated moderately to the amount of (D) amphetamine-induced rotations, whereas no significant correlation was found at 2 weeks post-lesion. Correlation coefficients (r) and statistical significance (P) were determined with Pearson correlation test (n = 12 (2 weeks) and n = 14 (4 weeks)).

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