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Table 1 Biodistribution of 68 Ga-NODAGA-RGD and 68 Ga-TRAP(RGD) 3 in tissues 90 min p.i

From: Comparison of cyclic RGD peptides for αvβ3 integrin detection in a rat model of myocardial infarction

  68Ga-NODAGA-RGD 68Ga-TRAP(RGD) 3  
Mean ± SD Mean ± SD
n= 9 n= 10 p Value
Blood 0.058 ± 0.02 0.101 ± 0.07 ns
Serum 0.094 ± 0.05 0.166 ± 0.12 ns
Remote myocardium 0.071 ± 0.03 0.154 ± 0.09 0.02
Apical myocardium 0.156 ± 0.06 0.353 ± 0.10 -
Muscle 0.035 ± 0.01 0.066 ± 0.03 0.028
Connective tissue 0.110 ± 0.05 0.190 ± 0.08 0.031
Wound 0.270 ± 0.24 0.256 ± 0.12 ns
Spleen 0.246 ± 0.16 0.415 ± 0.30 ns
Liver 0.230 ± 0.17 0.524 ± 0.61 ns
Kidney 1.102 ± 0.70 1.447 ± 0.51 ns
Urine 20.24 ± 6.40 35.10 ± 22.37 ns
  1. Ns, not significant; p.i., post-injection. Results presented as percentage of injected dose per gram of tissue (% ID/g). The apical myocardium contains both infarct and remote areas, as can be seen in processed transaxial sections for autoradiography.