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Table 3 Absorbed doses in the source organs

From: Evaluation of the biodistribution and radiation dosimetry of the 18F-labelled amyloid imaging probe [18F]FACT in humans

  Human Mouse
  All subjects (n= 6) Male Female  
   (n= 3) (n= 3)  
Organ     
Adrenal gland 1.96E01 ± 2.00 2.03E01 1.90E01 1.35E01
Brain 9.91 ± 1.82 8.95 1.09E01 4.17
Breasts 8.69 ± 2.55 6.68 1.07E01 9.90
Gallbladder wall 3.33E02 ± 2.51E02 2.16E02 4.50E02 1.68E01
Lower large intestine wall 2.52E01 ± 1.26E01 2.41E01 2.63E01 1.57E01
Small intestine 3.36E01 ± 3.07E01 2.07E01 4.64.E01 3.85E01
Stomach wall 1.61E01 ± 3.44 1.35E01 1.87E01 1.39E01
Upper large intestine wall 2.98E01 ± 1.50E01 2.36E01 3.59E01 1.83E01
Heart wall 1.62E01 ± 1.70 1.50E01 1.74E01 8.34
Kidneys 2.01E01 ± 4.30 1.85E01 2.17E01 1.32E01
Liver 7.75E01 ± 1.45E01 7.38E01 8.11E01 2.55E01
Lungs 1.46E01 ± 1.10 1.49E01 1.43E01 7.96
Muscle 1.03E01 ± 1.27 1.07E01 9.90 7.89
Ovary 1.67E01 ± 6.65 1.18E01 2.16E01 1.67E01
Pancreas 2.32E01 ± 3.11 2.17E01 2.47E01 1.45E01
Red marrow 1.31E01 ± 1.70 1.16E01 1.46E01 1.23E01
Osteogenic cells 1.60E01 ± 3.65 1.25E01 1.95E01 1.82E01
Skin 7.30 ± 1.39 5.99 8.60 8.70
Spleen 1.37E01 ± 2.48 1.27E01 1.48E01 7.83
Testis 7.32 ± 2.16 7.32 - 1.15E01
Thymus 1.00E01 ± 1.85 8.37 1.16E01 1.08E01
Thyroid 8.36 ± 1.38 8.86 7.86 1.10E01
Urinary bladder wall 2.23E01 ± 7.33 1.81E01 2.66E01 4.31E01
Uterus 1.67E01 ± 8.13 1.14E01 2.19E01 1.77E01
Total body 1.38E01 ± 1.63 1.22E01 1.53E01 1.22E01
Effective dose (μSv/MBq) 1.86E01 ± 3.74 1.64E01 2.09E01 1.48E01
  1. Averaged absorbed dose estimates (μGy/MBq) for the target organs from the whole-body PET data (n = 6) from experiments involving human subjects of [18F]FACT and mice of [18F]FACT. Average absorbed dose for male subjects (n = 3).