| |
Human
|
Mouse
|
|---|
| |
All subjects (n= 6)
|
Male
|
Female
| |
|---|
| | |
(n= 3)
|
(n= 3)
| |
|---|
|
Organ
| | | | |
|
Adrenal gland
|
1.96E01 ± 2.00
|
2.03E01
|
1.90E01
|
1.35E01
|
|
Brain
|
9.91 ± 1.82
|
8.95
|
1.09E01
|
4.17
|
|
Breasts
|
8.69 ± 2.55
|
6.68
|
1.07E01
|
9.90
|
|
Gallbladder wall
|
3.33E02 ± 2.51E02
|
2.16E02
|
4.50E02
|
1.68E01
|
|
Lower large intestine wall
|
2.52E01 ± 1.26E01
|
2.41E01
|
2.63E01
|
1.57E01
|
|
Small intestine
|
3.36E01 ± 3.07E01
|
2.07E01
|
4.64.E01
|
3.85E01
|
|
Stomach wall
|
1.61E01 ± 3.44
|
1.35E01
|
1.87E01
|
1.39E01
|
|
Upper large intestine wall
|
2.98E01 ± 1.50E01
|
2.36E01
|
3.59E01
|
1.83E01
|
|
Heart wall
|
1.62E01 ± 1.70
|
1.50E01
|
1.74E01
|
8.34
|
|
Kidneys
|
2.01E01 ± 4.30
|
1.85E01
|
2.17E01
|
1.32E01
|
|
Liver
|
7.75E01 ± 1.45E01
|
7.38E01
|
8.11E01
|
2.55E01
|
|
Lungs
|
1.46E01 ± 1.10
|
1.49E01
|
1.43E01
|
7.96
|
|
Muscle
|
1.03E01 ± 1.27
|
1.07E01
|
9.90
|
7.89
|
|
Ovary
|
1.67E01 ± 6.65
|
1.18E01
|
2.16E01
|
1.67E01
|
|
Pancreas
|
2.32E01 ± 3.11
|
2.17E01
|
2.47E01
|
1.45E01
|
|
Red marrow
|
1.31E01 ± 1.70
|
1.16E01
|
1.46E01
|
1.23E01
|
|
Osteogenic cells
|
1.60E01 ± 3.65
|
1.25E01
|
1.95E01
|
1.82E01
|
|
Skin
|
7.30 ± 1.39
|
5.99
|
8.60
|
8.70
|
|
Spleen
|
1.37E01 ± 2.48
|
1.27E01
|
1.48E01
|
7.83
|
|
Testis
|
7.32 ± 2.16
|
7.32
|
-
|
1.15E01
|
|
Thymus
|
1.00E01 ± 1.85
|
8.37
|
1.16E01
|
1.08E01
|
|
Thyroid
|
8.36 ± 1.38
|
8.86
|
7.86
|
1.10E01
|
|
Urinary bladder wall
|
2.23E01 ± 7.33
|
1.81E01
|
2.66E01
|
4.31E01
|
|
Uterus
|
1.67E01 ± 8.13
|
1.14E01
|
2.19E01
|
1.77E01
|
|
Total body
|
1.38E01 ± 1.63
|
1.22E01
|
1.53E01
|
1.22E01
|
|
Effective dose (μSv/MBq)
|
1.86E01 ± 3.74
|
1.64E01
|
2.09E01
|
1.48E01
|
- Averaged absorbed dose estimates (μGy/MBq) for the target organs from the whole-body PET data (n = 6) from experiments involving human subjects of [18F]FACT and mice of [18F]FACT. Average absorbed dose for male subjects (n = 3).
