In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106

EJNMMI Research

Table 3 Number of MS lesions and sizes of the 5 largest MS lesions in each subject

Subject	Number of MS lesions		Gd(+)	Sizes of five largest MS plaques (cm ³)
Subject	Total number	T2 and/or FLAIR high	Gd(+)	MSL1	MSL2	MSL3	MSL4	MSL5
A	14	13	2	0.3	0.2	0.1	0.1^a	0.1
B	20	18	6	6.2	4.3	2.9	1.6	0.7
C	42	42	4	1.3^a	1.2	1.1	1.0	0.8
D	25	25	3	0.8	0.6	0.6	0.6	0.5
E	31	31	20	0.6	0.6	0.4	0.4	0.2^a
F	29	29	3	15	4.0	1.7	1.6	1.5
G	10	10	5	10	1.8	0.2^a	0.1	0.1
H	30	30	3	0.7	0.4	0.4	0.3^a	0.2
I	10	10	2	0.7^a	0.3	0.2	0.1	0.1

^aGd-enhanced MS lesions. Other values were MS lesions which showed T2 and/or FLAIR high intensity but not Gd-enhanced MS lesions. As some MS lesions show both Gd-enhanced and T2 and/or FLAIR high intensity, the total number of MS lesions is not the sum of T2 and/or FLAIR high-intensity lesions and Gd-enhanced lesions.