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Table 1 Phantom activity distribution notations and their descriptions

From: Quantitative lung SPECT applied on simulated early COPD and humans with advanced COPD

  Distribution notation Coronal slice Number Distribution description Total reduction of ventilation (%)
Simulated normal Uniform 1 Homogeneous activity distribution 0
Simulated COPD 1 cm50% 10% evenly 2 Lesions with a diameter of 1 cm with 50% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume. 5
  1 cm50% 12% centred 3 Lesions with a diameter of 1 cm with 50% activity concentration, centred to the large bronchial tubes, occupying 12% of the total lung volume. 6
  1 cm0% 10% evenly 4 Lesions with a diameter of 1 cm with 0% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume. 10
  1 cm0% 12% centred 5 Lesions with a diameter of 1 cm with 0% activity concentration, centred to the large bronchial tubes, occupying 12% of the total lung volume. 12
  2 cm50% 10% evenly 6 Lesions with a diameter of 2 cm with 50% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume. 5
  2 cm0% 10% evenly 7 Lesions with a diameter of 2 cm with 0% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume. 10
  2 cm50% 48% evenly 8 Lesions with a diameter of 2 cm with 50% activity concentration, evenly distributed over the lung volume, occupying 48% of the total lung volume. 24
  2 cm25% 48% evenly 9 Lesions with a diameter of 2 cm with 25% activity concentration, evenly distributed over the lung volume, occupying 48% of the total lung volume. 36
  1. Coronal slices of the phantom include simulated motion artefacts.