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Table 1 Phantom activity distribution notations and their descriptions

From: Quantitative lung SPECT applied on simulated early COPD and humans with advanced COPD

 

Distribution notation

Coronal slice

Number

Distribution description

Total reduction of ventilation (%)

Simulated normal

Uniform

1

Homogeneous activity distribution

0

Simulated COPD

1 cm50% 10% evenly

2

Lesions with a diameter of 1 cm with 50% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume.

5

 

1 cm50% 12% centred

3

Lesions with a diameter of 1 cm with 50% activity concentration, centred to the large bronchial tubes, occupying 12% of the total lung volume.

6

 

1 cm0% 10% evenly

4

Lesions with a diameter of 1 cm with 0% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume.

10

 

1 cm0% 12% centred

5

Lesions with a diameter of 1 cm with 0% activity concentration, centred to the large bronchial tubes, occupying 12% of the total lung volume.

12

 

2 cm50% 10% evenly

6

Lesions with a diameter of 2 cm with 50% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume.

5

 

2 cm0% 10% evenly

7

Lesions with a diameter of 2 cm with 0% activity concentration, evenly distributed over the lung volume, occupying 10% of the total lung volume.

10

 

2 cm50% 48% evenly

8

Lesions with a diameter of 2 cm with 50% activity concentration, evenly distributed over the lung volume, occupying 48% of the total lung volume.

24

 

2 cm25% 48% evenly

9

Lesions with a diameter of 2 cm with 25% activity concentration, evenly distributed over the lung volume, occupying 48% of the total lung volume.

36

  1. Coronal slices of the phantom include simulated motion artefacts.