Blood clearance in NMRI mice and tumor uptake and tumor-to-blood ratio in A549 lung tumor-bearing mice. Blood clearance of 131I-labeled chFab, chF(ab')2, and chAb 14C5 in NMRI mice (a). Tumor uptake (%ID/g) (b) and tumor-to-blood ratio (c) of 131I-labeled chAb, chF(ab')2, and chFab 14C5 in A549 lung tumor-bearing mice. Values are corrected for decay of the radionuclide. Data are expressed as mean ± SD (n = 3 to 5).