Figure 3

Time-activity curves in various brain regions, following IV injection of 15±4 MBq [¹¹ C]prucalopride. Time-activity curves in various brain region, measured using PET, following IV injection of 15 ± 4 MBq [¹¹C]prucalopride (SA 65 ± 5GBq·μmol⁻¹). Open triangles (with dashed line) represent SUVs at baseline, and solid triangles (with solid line) represent SUVs after tariquidar pre-treatment (15 mg·kg⁻¹ IV). In both cases n = 4.