Table 1 Group characteristics at day 0 and injected activities (average values and ranges)
From: Successful radioimmunotherapy of established syngeneic rat colon carcinoma with 211At-mAb
Treatment group | Body weight (g) | Tumor volume (mm 3) | Injected activity (MBq) | IA/kg body weight (MBq/kg) |
|---|---|---|---|---|
Controls (unlabeled BR96) | ||||
Tumor (n = 6) | 290 (282 to 300) | 520 (282 to 640) | - | - |
Non-tumor (n = 3) | 289 (281 to 296) | - | - | - |
2.5 MBq 211At-BR96 | ||||
Tumor (n = 6) | 272 (269 to 278) | 475 (256 to 640) | 2.5 (2.5 to 2.6) | 9.3 (9.0 to 9.6) |
Non-tumor (n = 3) | 276 (271 to 278) | - | 2.4 (2.4 to 2.4) | 8.8 (8.7 to 8.9) |
5 MBq 211At-BR96 | ||||
Tumor (n = 6) | 259 (247 to 266) | 371 (176 to 520) | 5.0 (4.9 to 5.1) | 19.2 (18.3 to 19.9) |
Non-tumor (n = 3) | 264 (259 to 267) | - | 4.8 (4.6 to 4.9) | 18.0 (17.5 to 18.3) |