Comparative results using SPM-A, SPM-P, and visual analyses. Comparative results using SPM-A (adult control group), SPM-P (pediatric pseudo-control group) and visual analyses in a 4 year old patient. In this 4-year-old patient with positive MRI and seizure onset zone (SOZ) in the left insula, visual analysis (image C) shows a left insular hypometabolic area (axial slice). SPM-P (image B, SPM glass brain) identifies a hypometabolic cluster in the same area. SPM-A (image A, SPM glass brain) also identifies this cluster, but also shows several additional hypometabolic artifacts mainly located within the frontal cortex, ipsi- and contralaterally.