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Table 3 Overview of injected doses of [ 11 C]AF150(S) and AF150(S)

From: [11C]AF150(S), an agonist PET ligand for M1 muscarinic acetylcholine receptors

Cold AF150(S) co-injected per rat (nmol) Number [ 11C]AF150(S) injected radioactivity (MBq) Specific activity of cold diluted [ 11C]AF150(S) at injection (GBq μmol −1) AF150(S) total dose (nmol kg −1)
0 12 16.9 ± 0.8 82.9 ± 8.4 0.7 ± 0.1
1 4 17.8 ± 0.3 6.4 ± 0.0 10.9 ± 0.3
5 4 15.7 ± 2.1 2.4 ± 0.3 21.7 ± 2.2
15 4 18.2 ± 1.1 1.1 ± 0.1 49.1 ± 1.2