Table 3 Overview of injected doses of [ 11 C]AF150(S) and AF150(S)
From: [11C]AF150(S), an agonist PET ligand for M1 muscarinic acetylcholine receptors
Cold AF150(S) co-injected per rat (nmol) | Number | [ 11C]AF150(S) injected radioactivity (MBq) | Specific activity of cold diluted [ 11C]AF150(S) at injection (GBq μmol −1) | AF150(S) total dose (nmol kg −1) |
|---|---|---|---|---|
0 | 12 | 16.9 ± 0.8 | 82.9 ± 8.4 | 0.7 ± 0.1 |
1 | 4 | 17.8 ± 0.3 | 6.4 ± 0.0 | 10.9 ± 0.3 |
5 | 4 | 15.7 ± 2.1 | 2.4 ± 0.3 | 21.7 ± 2.2 |
15 | 4 | 18.2 ± 1.1 | 1.1 ± 0.1 | 49.1 ± 1.2 |