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Table 2 Nuclear medicine imaging studies with VAP-1 targeting agents

From: Nuclear imaging of inflammation: homing-associated molecules as targets

Imaging agent

Imaged condition

Reference

123I-labeled anti-human-VAP-1 mAb 1B2

Animal models of skin inflammation and aseptic arthritis

[31]

68Ga-labeled VAP-1 binding peptide, 68Ga-DOTAVAP-P1

Animal model of osteomyelitis

[37, 38]

68Ga-labeled VAP-1 binding peptide, 68Ga-DOTAVAP-P1

Animal model of sterile skin inflammation and pancreatic adenocarcinoma xenograft in rat

[39]

68Ga-labeled VAP-1 binding peptide, 68Ga-DOTAVAP-PEG-P1

Animal model of sterile skin inflammation in rat

[40]

68Ga-labeled VAP-1 binding peptide, 68Ga-DOTA-Siglec-9 peptide

Animal model of sterile skin inflammation in rat, DNBC-induced skin inflammation in hVAP-1 transgenic mouse and VAP-1 knockout mouse

[41]