Table 2 Tissue distribution volumes of different VOIs
Brain region (V t) | Hemisphere | Control (N = 4) | KASE (N = 4) | Increase (%) |
|---|---|---|---|---|
Frontal cortex | Left | 5.4 ± 1.0 | 11.3 ± 2.4§ | 108 |
|  | Right | 5.7 ± 1.2 | 11.2 ± 2.4§ | 98 |
Striatum | Left | 2.8 ± 0.6 | 8.0 ± 1.2* | 180 |
|  | Right | 3.0 ± 0.5 | 7.8 ± 1.1* | 156 |
Parietal cortex | Left | 4.5 ± 0.6 | 9.5 ± 1.1§ | 110 |
|  | Right | 4.9 ± 0.8 | 11.6 ± 2.0* | 136 |
Hippocampus | Left | 3.6 ± 0.5 | 9.1 ± 1.1** | 154 |
|  | Right | 3.6 ± 0.4 | 9.4 ± 1.6* | 159 |
Thalamus | Left | 2.6 ± 0.5 | 7.0 ± 1.8§ | 173 |
|  | Right | 2.8 ± 0.5 | 7.1 ± 1.4* | 155 |
Hypothalamus |  | 4.0 ± 0.7 | 8.2 ± 1.4§ | 104 |
Amygdala | Left | 5.3 ± 0.8 | 20.6 ± 2.8** | 288 |
|  | Right | 6.1 ± 0.7 | 23.4 ± 4.8* | 284 |
Occipital cortex | Left | 9.8 ± 3.4 | 15.1 ± 3.5 | 53 |
|  | Right | 9.3 ± 1.4 | 15.0 ± 1.4* | 62 |
Colliculi | Left | 4.0 ± 1.0 | 5.8 ± 1.1 | 44 |
|  | Right | 4.1 ± 1.1 | 6.9 ± 1.8 | 70 |
Brainstem |  | 4.7 ± 0.8 | 6.7 ± 1.0 | 41 |
Pons |  | 4.2 ± 0.9 | 7.5 ± 1.8 | 78 |
Cerebellum |  | 7.5 ± 0.8 | 10.6 ± 1.3 | 43 |