Figure 3

[¹²⁵ I]SGMIB-MNT nuclear kinetics. Western blot analysis for (a) α-tubulin (a cytoplasmic protein) and (b) histone deacytalase-1 (nuclear protein) in cytoplasmic fraction or nuclear fraction from A431 cells. (c) Nuclear kinetics of [¹²⁵I]SGMIB-MNT in A431 cells (circles and squares refer to separate experiments). For each data point, the experiment was done in triplicate with bars representing the standard error of mean.