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EJNMMI Research

Table 2 Number of human volunteers ( n ), weight at time of PET, injected doses (average ± standard deviation) of ( R )-[ 11 C]verapamil for baseline, and post-inhibition scans after tariquidar (2 mg/kg) treatment

From: Pharmacokinetic modeling of P-glycoprotein function at the rat and human blood–brain barriers studied with (R)-[11C]verapamil positron emission tomography

 

Healthy volunteers and 2 mg/kg tariquidar treated

Number

5

Body weight (kg)

74±5

Baseline (R)-[11C]verapamil (MBq)

379±11

I.V. injection time (sec)

51±10

Post-inhibition (R)-[11C]verapamil (MBq)

389±15

I.V. injection time (sec)

43±11

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