Skip to main content


Figure 4 | EJNMMI Research

Figure 4

From: Pharmacokinetic modeling of P-glycoprotein function at the rat and human blood–brain barriers studied with (R)-[11C]verapamil positron emission tomography

Figure 4

WB ( R )-[11 C]verapamil time-activity curves in humans. Average ± standard deviation (R)-[11C]verapamil concentration-time curves in human WB gray matter expressed as SUV at baseline (open symbols) and at post-inhibition (full symbols). Tariquidar (2 mg/kg) was administered 40 min after the start of the baseline scan as an infusion over 30 min (arrow).

Back to article page