WB ( R )-[11
C]verapamil time-activity curves in rats. Average ± standard deviation (R)-[11C]verapamil concentration-time curves in rat WB expressed as SUV for naïve (squares) and 48-h post SE (circles) animals at baseline (open symbols) and at post-inhibition (full symbols). Tariquidar (3 mg/kg) was administered 60 min after the start of the baseline scan as an I.V. bolus over 60 sec (arrow).