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Table 1 Correlation of clinical and SPECT/CT findings with consecutive therapeutic change

From: Diagnostic and therapeutic impact of SPECT/CT in patients with unspecific pain of the hand and wrist

Patients

Clinical symptoms

Estimated diagnosis

SPECT/CT diagnosis and therapy

1

Persistent pain after arthroplasty CMC-1 and revision with partial resection of the trapezium bone

Possible persistent osseous reaction after arthroplasty

Significant uptake in MC-1 base and the trapezium bone

Therapy: additional infiltration

4

Persistent posttraumatic wrist pain 6 months after undislocated radius fracture

Posttraumatic osseous lesion

Persistent posttraumatic reactive bone remodeling at fracture site, no significant osteoarthritis

Therapy: additional occupational therapy

9

Unclear pain in CMC-1 with pain, swelling, and redness

Unclear, ganglion cyst (detected in MRI) not correlating with clinical symptoms

Mild uptake in the hamate bone and distal radius, no osteoarthritic changes

Therapy: immobilization and additional occupational therapy

10

Unclear persistent wrist pain and pain in both Dig-I for several years

Osteoarthritis

No significant osteoarthritis, no signs of inflammatory arthritis

Therapy: rheumatologic follow-up and supportive therapy

11

Unclear right-sided wrist pain (ulnocarpal)

Unclear, possible insertion tendinosis

No pathologic osseous findings, thus exclusion of possible diagnosis (clinically possible tendinosis)

Therapy: immobilization, infiltration, and occupational therapy

16

Unclear pain in right CMC-1, no trauma

Unclear

Uptake in both STT joints, beginning (activated) osteoarthritis

Therapy: occupational therapy

19

Arthritic right-sided wrist pain, no trauma

Triscaphoid osteoarthritis/possible irritation of the STT joint

Moderate bone remodeling of the right RC and SL joints without significant osteoarthritis, no STT osteoarthritis

Therapy: occupational therapy, change of working place environment, and NSAID

20

Persisting left-sided wrist pain during flexion, no trauma

Unclear

Persisting bone growth, no bony lesion, exclusion of other differential diagnosis

22

Unclear right-sided radiocarpal wrist pain 1 year after trauma

Posttraumatic osseous/osteoarthritic lesion

Persistent bone remodeling at fracture site

Therapy: occupational therapy

24

Radiocarpal right-sided pain for more than 1 year, no trauma

Unclear, MRI findings did not explain clinical symptoms

Elevated radiocarpal bone metabolism, together with clinical findings suggestive for tendovaginitis

Therapy: immobilization, infiltration, and subsequent surgery

25

Carpal pain after scaphoid pseudoarthrosis, CT shows no persisting fracture

Triscaphoid osteoarthritis

Persistent bone remodeling in former fracture zone, no ST uptake but slight stress reaction radio-scaphoidal

Therapy: surgery

29

Left-sided wrist pain while grabbing and lifting

Tendinitis

Osteomalacia of the lunate bone

Therapy: surgery

34

Pain in the CMC-1 and MC-1 base, wrist trauma 20 years ago

Osteoarthritis STT joint

Posttraumatic intraosseous ganglion cyst in the right scaphoid

Therapy: surgery recommended, yet not operated

36

Persistent pain after posttraumatic arthrodesis IP-I

CRPS

Persistent bone remodeling in arthrodesis, osteoarthritis CMC-2 joint, no CRPS

Therapy: supportive and occupational therapy

37

Persitent pain in CMC-1 joints after trapezectomy and right arthroplasty >3 years ago

CMC-1 osteoarthritis

Severely activated CMC-1 osteoarthritis

Therapy: revision surgery

46

Pain after scaphoid fracture and consolidated pseudoarthrosis

RC osteoarthritis

No RC osteoarthritis, vital scaphoid fragment with bone remodeling

Therapy: revision surgery

49

Persistent pain in the distal ulna after distorsion >8 months ago

Ganglion cyst (diagnosed in MRI) was suspected to cause pain

Reactive elevation of bone metabolism at ulnar styloid (insertion of TFCC), ganglion cyst as the cause of clinical symptoms was excluded

Therapy: immobilization, infiltration, and shaving during later course of disease

50

Carpal pain, known radiopalmar ganglion cyst

Possible additional STT osteoarthritis

Activated osteoarthritis in multiple IP and MCP joints, exclusion of STT osteoarthritis

Therapy: ganglion resection

51

Left-sided carpal pain with painful bump

Carpal boss MCP III with reactive bony lesion and possible additional degenerative joint lesions

Carpal boss MCP-III with osseous reaction

Therapy: surgical resection without additional arthrodesis (no additional joint degenerations)

  1. CMC, carpometacarpal joint; CRPS, complex regional pain syndrome; IP, interphalangeal joint; MC, metacarpal joint; MCP, metacarpophalangeal joint; PIP, proximal interphalangeal joint; RC, radiocarpal joint; STT, scaphoid-trapezium-trapezoideum joint.