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Figure 2 | EJNMMI Research

Figure 2

From: Single-photon emission computed tomography of spontaneous liver metastasis from orthotopically implanted human colon cancer cell line stably expressing human sodium/iodide symporter reporter gene

Figure 2

In vivo studies using mouse subcutaneous xenograft model. (A) Rate of tumor formation, (B) time to tumor formation, (C) SPECT/CT images of a representative mouse. SG, Th, St, and Bl (arrowheads) indicate the salivary glands, thyroid, stomach, and urinary bladder, respectively. Lt, left; MIP, maximum intensity projection; Rt, right. (D) 99mTcO4 uptake levels of subcutaneous xenografts. Cell lines A, B, and C (black bars, arrows) were HCT116 stably transfected with pcDNA3-NIS, and cell line N (white bar, arrow) was the untransfected negative control.

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