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EJNMMI Research
Figure 6 | EJNMMI Research

Figure 6

From: Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[11 C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([11 C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1

Figure 6

Fraction of [11 C]  N  -methyl-SSR504734 in the plasma during PET measurements. Percentage of unmetabolized [11 C]N-methyl-SSR504734 in the plasma of a cynomolgus monkey at baseline and pretreatment conditions (0.5 or 1.5 mg/kg of SSR504734) (A). HPLC analysis of plasma samples at 4 (C) and 90 min (D) after injection of [11 C]N-methyl-SSR504734 at baseline.

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