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Figure 5 | EJNMMI Research

Figure 5

From: Pharmacodynamic analysis of tumour perfusion assessed by 15O-water-PET imaging during treatment with sunitinib malate in patients with advanced malignancies

Figure 5

Correlation between reduction in tumour perfusion and trough levels of total drug, VEGF, and sVEGFR-2. Potential correlations between percent reduction in tumour perfusion and day 15 trough levels of total drug (sunitinib plus SU12662; p > 0.05) (a), change in plasma VEGF levels (p = 0.05) (b), and change in plasma sVEGFR-2 levels (p > 0.05) (c). D15:D1, day 15:day 1 ratio.

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