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Table 2 18F-activity uptake 40 min after injection of [18F]CFT into the brains of control and pretreated rats

From: [18F]CFT synthesis and binding to monoamine transporters in rats

Brain region Control
n= 6
GBR12909
n= 7
Nisoxetine
n= 6
Fluoxetine
n= 6
Striatum 1.55 ± 0.78 0.49 ± 0.18* 1.48 ± 0.22 1.38 ± 0.75
Locus coeruleus 0.67 ± 0.29 0.37 ± 0.11** 0.23 ± 0.05* 0.47 ± 0.16
Frontal cortex 0.32 ± 0.08 0.23 ± 0.04 0.26 ± 0.03 0.33 ± 0.13
Cerebellum 0.20 ± 0.04 0.15 ± 0.04 0.17 ± 0.02 0.23 ± 0.09
  1. *p < 0.01 compared with control;**p < 0.05 compared with control. Uptake values are in percent injected dose per gram tissue. All values are means ± SD. The effect of pretreatment was compared with the uptake values of control rats. Means were considered significantly different when p < 0.05.