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EJNMMI Research

Table 2 18F-activity uptake 40 min after injection of [18F]CFT into the brains of control and pretreated rats

From: [18F]CFT synthesis and binding to monoamine transporters in rats

Brain region

Control

n= 6

GBR12909

n= 7

Nisoxetine

n= 6

Fluoxetine

n= 6

Striatum

1.55 ± 0.78

0.49 ± 0.18*

1.48 ± 0.22

1.38 ± 0.75

Locus coeruleus

0.67 ± 0.29

0.37 ± 0.11**

0.23 ± 0.05*

0.47 ± 0.16

Frontal cortex

0.32 ± 0.08

0.23 ± 0.04

0.26 ± 0.03

0.33 ± 0.13

Cerebellum

0.20 ± 0.04

0.15 ± 0.04

0.17 ± 0.02

0.23 ± 0.09

  1. *p < 0.01 compared with control;**p < 0.05 compared with control. Uptake values are in percent injected dose per gram tissue. All values are means ± SD. The effect of pretreatment was compared with the uptake values of control rats. Means were considered significantly different when p < 0.05.
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