Code
|
hsst1
|
hsst2
|
hsst3
|
hsst4
|
hsst5
|
---|
SS14
|
1.9 ± 0.5 (5)
|
0.7 ± 0.2 (5)
|
3.3 ± 1.7 (4)
|
1.6 ± 0.8 (4)
|
4.2 ± 0.7 (3)
|
SS28
|
2.7 ± 0.5 (3)
|
2.5 ± 0.1 (3)
|
2.2 ± 0.6 (3)
|
2.1 ± 0.4 (3)
|
2.0 ± 0.2 (3)
|
AT1S
|
5.1 ± 1.4 (3)
|
2.8 ± 0.3 (3)
|
1.8 ± 0.6 (3)
|
2.5 ± 0.6 (3)
|
17 ± 3 (3)
|
AT2S
|
14 ± 2 (3)
|
1.5 ± 0.3 (3)
|
2.4 ± 0.5 (3)
|
3.7 ± 0.7 (3)
|
12 ± 2 (3)
|
- Mean ± SEM (numbers in parentheses = number of experiments). The profile for the human sst1-5 receptors was determined by receptor autoradiography experiments; [Leu8,DTrp22,125I-Tyr25]SS28 was used as the radioligand and SS14 and SS28 as control compounds.