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Table 1 Overview of published SPECT investigations of myocardial perfusion using MIBI and/or TETRO in mice and rats

From: Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT

Author Species Tracer Injection route Activity (MBq) Time point Scan length
Acton PD Rats 99mTc-MIBI Tail vein 37 1 h PI 30 min
(2006); [9]       
Constantinesco A Mice 99mTc-tetrofosmin Femoral vein 350-450 15-20 min PI 48 Projections with 300 beats/projections
(2005); [12]       
Hatada K Rats 99mTc-MIBI Saphenous vein 37,7-48,1 2,30, and 60 min PI 5 min
(2004); [14]   99mTc-tetrofosmin     
Liu Z Rats 99mTc-MIBI Jugular vein 111-148 0 PI List mode
(2010); [13]       
Strydhorst JH Rats 99mTc-tetrofosmin Tail vein 78 ± 15 30 min p.i 30 min
(2011); [11]       
Wollenweber T Mice 99mTc-MIBI Tail vein 370 45 min PI 30 min
(2010); [10]       
  1. Note the broad range in injected doses and acquisition time points after tracer injection