PET scans. One transverse slice of the patient No. 6 showing the metabolic sites of its large necrotic tumour that received different absorbed dose. The FDG uptake of the metabolic sites 1,2,3,5, that were well targeted by the microspheres, decreased between the FDG-BL and FDG-FU scans, while the metabolic site 4 not targeted by the microspheres rapidly increased in FDG uptake and in size as well, to become a new large necrotic metastatic site. The VOI on the FDG-FU scan was increased to encompass all the FDG activity originating from the increased site 4.