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EJNMMI Research
Figure 2 | EJNMMI Research

Figure 2

From: Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects

Figure 2

Metabolism of [11 C](R)-PK11195. (A) Radiochromatogram from gradient HPLC analysis of human plasma after i.v. injection of [11C](R)-PK11195 (peak III). Peaks I and II represent labelled metabolites that are more polar than unchanged [11C](R)-PK11195. (B) Time course for the fraction (%) of radioactivity in plasma that represents unchanged [11C](R)-PK11195 and its metabolites in six healthy human subjects (mean, SD).

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