Time-radioactivity curves for [ N -methyl-11
C]mirtazapine in the bloodstream and the brain. (A) Percentage of [11C]-derived radioactivity corresponding to the unmetabolized [N-methyl-11C]mirtazapine in the bloodstream of each subject after intravenous injection. The five symbols correspond to the five subjects. (B) Decay-corrected time-radioactivity curves for [11C]mirtazapine in the plasma after intravenous bolus injection in one subject. (C) Decay-corrected time-activity curves for [11C]mirtazapine in brain regions in one subject.