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Table 2 Mean, median, minimum, and maximum values of metabolic volumes and their median differences for NSCLC

From: Measurement of metabolic tumor volume: static versus dynamic FDG scans

Delineation method Volume obtained from SUV image (mL) Volume obtained from Patlak image (mL) % Median differencea P value P valueb
  Mean Median Min Max Mean Median Min Max    
VOI50 84.2 6.9 1.2 950.2 7.7 2.7 0.7 74.4 58.7 < 0.001 < 0.001
VOI70 4.9 1.5 0.5 50.2 2.5 1.1 0.3 23.7 48.0 < 0.001 < 0.001
VOIA41 22.7 5.2 1.2 294.4 10.9 3.5 0.9 95.2 25.8 < 0.001 < 0.001
VOIA50 8.8 2.4 0.6 97.0 6.6 2.4 0.5 70.6 15.0 < 0.001 < 0.001
VOIA70 2.1 0.5 0.1 23.4 1.8 0.8 0.2 19.9 -25.0 0.044 0.044
VOIRTL 10.4 3.6 0.4 101.9 7.7 3.1 0.3 73.1 15.6 < 0.001 < 0.001
VOISchaefer 17.2 5.1 1.0 125.7 13.8 4.2 0.9 104.2 14.3 < 0.001 < 0.001
GradWT1 12.3 3.9 1.4 163.2 10.4 5.4 1.6 50.9 1.9 0.725 0.324
GradWT2 5.8 2.7 0.6 63.2 3.7 2.1 0.5 28.2 18.2 < 0.001 0.001
  1. aThe percentage difference was defined as Volum e SUV Volum e Patlak  -  1 × 100 % . The average tumor-to-background ratio was 5.3 (range 2.7 to 12.7) and 18.8 (range 6.1 to 81.0) when derived from SUV and Patlak images, respectively. bWithout visual outliers. SUV, standardized uptake value; min, minimum; max, maximum; VOI, volumes of interest; GradWT1, gradient-based watershed first approach; GradWT2, gradient-based watershed second approach.