Figure 5
From: Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets
Biodistribution of 89 Zr-cetuximab-IRDye800CW in tumor-bearing mice. Biodistribution of intravenously injected 89Zr-cetuximab and 89Zr-cetuximab-IRDye800CW (0.5, 1, and 2 eq) in A431 xenograft-bearing nude mice at 24 (A), 48 (B), and 72 (C) h after injection. Bars marked with an asterisk have an uptake that is significantly (P ≤ 0.05) different from the uptake of 89Zr-cetuximab. Data are presented as %ID/g ± SD.