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Table 2 Ex vivo measures of 18F-FDG in IBAT and WAT

From: Quantitative assessment of brown adipose tissue metabolic activity and volume using 18F-FDG PET/CT and β3-adrenergic receptor activation

Groups IBAT WAT Ratio (IBAT/WAT)
  Autorad a
(10 6 DLU/mm 2 )
Autopsy b
(kBq/g/(MBq/kg))
Autorad a
(10 6 DLU/mm 2 )
Autopsy b
(kBq/g/(MBq/kg))
Autorad a
(10 6 DLU/mm 2 )
Autopsy b
(kBq/g/(MBq/kg))
Control 1.6 ± 0.2** 4.3 ± 0.4** 0.5 ± 0.1 1.6 ± 0.1 3.2 ± 0.2 2.7 ± 0.1
CL316,243-treated 13.7 ± 0.1*, ** 68.1 ± 18.0*, ** 1.1 ± 0.3* 2.4 ± 0.2* 12.5 ± 3.3* 27.6 ± 5.5*
  1. aResults of autoradiography in transverse sections of IBAT and the surrounding WAT mean ± SD, n = 3; *p < 0.05 as compared to the control; **p < 0.05 as compared to WAT; bResults of counted radioactivity concentrations in autopsied IBAT and the surrounding WAT mean ± SD, n = 3; *p < 0.05 as compared to the control; **p < 0.05 as compared to WAT. IBAT, interscapular brown adipose tissue; WAT, white adipose tissue; CL316,243, (R, R)-5-[2-[2,3-(3-chlorphenyl)-2-hydroxyethyl-amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate, disodium salt.