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Table 2 Ex vivo measures of 18F-FDG in IBAT and WAT

From: Quantitative assessment of brown adipose tissue metabolic activity and volume using 18F-FDG PET/CT and β3-adrenergic receptor activation

Groups

IBAT

WAT

Ratio (IBAT/WAT)

 

Autorad a

(10 6 DLU/mm 2 )

Autopsy b

(kBq/g/(MBq/kg))

Autorad a

(10 6 DLU/mm 2 )

Autopsy b

(kBq/g/(MBq/kg))

Autorad a

(10 6 DLU/mm 2 )

Autopsy b

(kBq/g/(MBq/kg))

Control

1.6 ± 0.2**

4.3 ± 0.4**

0.5 ± 0.1

1.6 ± 0.1

3.2 ± 0.2

2.7 ± 0.1

CL316,243-treated

13.7 ± 0.1*, **

68.1 ± 18.0*, **

1.1 ± 0.3*

2.4 ± 0.2*

12.5 ± 3.3*

27.6 ± 5.5*

  1. aResults of autoradiography in transverse sections of IBAT and the surrounding WAT mean ± SD, n = 3; *p < 0.05 as compared to the control; **p < 0.05 as compared to WAT; bResults of counted radioactivity concentrations in autopsied IBAT and the surrounding WAT mean ± SD, n = 3; *p < 0.05 as compared to the control; **p < 0.05 as compared to WAT. IBAT, interscapular brown adipose tissue; WAT, white adipose tissue; CL316,243, (R, R)-5-[2-[2,3-(3-chlorphenyl)-2-hydroxyethyl-amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate, disodium salt.