Figure 6

Representative sections of anterior tibialis muscles stained for RAGE (brown chromagen) and displayed at 20×. The left set of images shows sections from a left (L) ischemic hindlimb (top) and control right (R) limb (bottom) from a WT non-diabetic (NDM) mouse 7 days (D) after femoral artery ligation. The center set of images shows sections from a left ischemic hindlimb (top) and control right limb (bottom) from a WT diabetic (DM) mouse 7 days after femoral artery ligation. The right set of images shows sections from a left ischemic hindlimb from a RAGE^-/- non-diabetic mouse at day 7 after femoral artery ligation (top) and from a RAGE^-/- diabetic mouse at day 7 after femoral artery ligation (bottom).