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EJNMMI Research

Table 3 Myocardial blood flow values according to paraoxonase genotype subgroups

From: Effects of paraoxonase activity and gene polymorphism on coronary vasomotion

Variable (n= 18)

Group 1a

(n= 7)

Group 2b

(n= 5)

Group 3c

(n= 6)

p value*

Rest-MBF (mL/min/g)

1.2 ± 0.4

1.1 ± 0.3

1.0 ± 0.5

0.56

CPT-MBF (mL/min/g)

1.4 ± 0.5

1.5 ± 0.5

1.2 ± 0.3

0.48

MBF difference CPT-rest (mL/min/g)

0.2 ± 0.3

0.4 ± 0.3

0.2 ± 0.5

0.55

MBF difference CPT-rest (%)

18 ± 17

36 ± 16

40 ± 51

0.46

Stress-MBF (mL/min/g)

3.0 ± 0.8

2.5 ± 0.6

2.5 ± 0.6

0.33

MFR (1)

2.7 ± 0.7

2.4 ± 0.3

3.1 ± 1.1

0.35

  1. *p Values were calculated using one-way analysis of variance. aGroup1 = wild type + LM/QR heterozygotes; bgroup 2 = MM homozygotes; cgroup 3 = RR homozygotes. CPT, cold pressor test; MBF, myocardial blood flow; MFR, myocardial flow reserve; MM, methionine-methionine; RR, arginine-arginine.
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