Table 2 Laboratory analyses according to paraoxonase genotype subgroups
From: Effects of paraoxonase activity and gene polymorphism on coronary vasomotion
Variable (n= 18) | Group 1a (n= 7) | Group 2b (n= 5) | Group 3c (n= 6) | p value* |
|---|---|---|---|---|
LDL-cholesterol (mmol/L) | 2.3 ± 0.9 | 2.5 ± 0.6 | 2.1 ± 0.3 | 0.71 |
HDL-cholesterol (mmol/L) | 1.1 ± 0.3 | 1.0 ± 0.1 | 1.3 ± 0.3 | 0.16 |
Triglyceride levels (mmol/L) | 2.1 ± 0.7 | 1.7 ± 0.8 | 2.1 ± 2.5 | 0.90 |
Fastening insulin (μU/mL) | 26.2 ± 15.0 | 23.2 ± 17.9 | 40.3 ± 55.0 | 0.67 |
Fastening glucose (mmol/L) | 8.3 ± 3.7 | 8.7 ± 2.5 | 7.7 ± 2.9 | 0.86 |
HOMA-IR (1) | 11.0 ± 10.9 | 8.8 ± 6.8 | 18.6 ± 32.8 | 0.70 |
hsCRP (mg/L, normal < 5 mg/L) | 5.6 ± 7.1 | 5.6 ± 5.7 | 1.6 ± 1.9 | 0.36 |
PON1 activity (U/L) | 51.1 ± 35.3 | 11.9 ± 6.7 | 168 ± 27 | <0.0001 |
Arylesterase (U/L) | 46.5 ± 14.0 | 36.2 ± 8.9 | 45.9 ± 5.5 | 0.22 |
Ratio hsCRP/PON1 × 1,000 (mg/U) | 365 ± 774 | 401 ± 254 | 10.0 ± 12.5 | 0.37 |