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Figure 5 | EJNMMI Research

Figure 5

From: Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

Figure 5

Immunolocalization of anti-CEA scFv-Fc (H310A) antibody fragment after tail vein injection into HPAF-II tumor-bearing mice. At ×20 magnification, (a) H&E-stained section, (b) negative control; slide incubated with only with secondary HRP-conjugated goat anti-mouse IgG (Fc specific) antibody, (c) positive control; slide incubated with primary mouse anti-CEA antibody and secondary HRP-conjugated goat anti-mouse IgG (Fc specific) antibody, (d) slide incubated with mouse anti-human IgG (Fc specific) antibody and HRP-conjugated goat anti-mouse IgG (Fc specific) antibody.

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