Figure 4
From: Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment
MicroPET and MicroCT images of a representative mouse from each group at 20 h. After tail vein injection showing targeting of each xenograft with the anti-CEA scFv-Fc (H310A) antibody fragment. Note CEA-positive xenografts (arrow) were not in the same plane as CEA-negative xenografts although present on all mice except HPAF tumor bearing mice. (a) BxPC3 tumor xenograft mouse, (b) Capan-1 tumor xenograft mouse, (c) HPAF-II tumor xenograft mouse. (d) Table with the corresponding measured radioactivity of each tissue. Values are represented as percent of injected dose per gram of tissue (%ID/g).