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Figure 2 | EJNMMI Research

Figure 2

From: Experimental α-particle radioimmunotherapy of breast cancer using 227Th-labeled p-benzyl-DOTA-trastuzumab

Figure 2

Absorbed radiation doses to normal tissues and tumor xenografts. Absorbed radiation dose in tumor and normal organs of mice injected with 227Th-trastuzumab (a) or 227Th-rituximab (b). Cumulated activities were calculated from biodistribution curves and multiplied with the mean energy of α-particles from 227Th, 223Ra, and daughters. Biodistribution data of 227Th-trastuzumab and 227 Th-rituximab were normalized to 400 kBq/kg bodyweight.

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