Figure 2

Absorbed radiation doses to normal tissues and tumor xenografts. Absorbed radiation dose in tumor and normal organs of mice injected with ²²⁷Th-trastuzumab (a) or ²²⁷Th-rituximab (b). Cumulated activities were calculated from biodistribution curves and multiplied with the mean energy of α-particles from ²²⁷Th, ²²³Ra, and daughters. Biodistribution data of ²²⁷Th-trastuzumab and ²²⁷ Th-rituximab were normalized to 400 kBq/kg bodyweight.