Figure 1From: P-glycoprotein at the blood-brain barrier: kinetic modeling of 11C-desmethylloperamide in mice using a 18F-FDG μPET scan to determine the input function Radiosynthesis of 11 C-desmethylloperamide. Didesmethylloperamide is methylated with 11CH3I to obtain 11C-desmethylloperamide in the presence of tetrabutylammoniumhydroxide, dimethylsulfoxide, and dimethylformamide.Back to article page