EJNMMI Research

Table 1 Pharmacokinetic parameters of the VAP-1-targeting ⁶⁸Ga-DOTA-peptides

From: Mini-PEG spacering of VAP-1-targeting ⁶⁸Ga-DOTAVAP-P1 peptide improves PET imaging of inflammation

	⁶⁸Ga-DOTAVAP-P1	⁶⁸Ga-DOTAVAP-PEG-P1	P value
Elimination t _1/2 (min)	13.4 ± 1.8	28.0 ± 10.7	NS (0.079)
k _el (1/min)	0.05 ± 0.01	0.02 ± 0.01	0.018
AUC (min*kBq/ml)	950 ± 170	2,400 ± 68	0.022
CL (ml/min)	0.017 ± 0.001	0.008 ± 0.002	0.006

k _el, elimination rate constant; AUC, area under curve; CL, clearance; NS, not significant.

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